Since the mid-1870s, the Jewish community had been collecting funds for the construction of a new synagogue. Head Hirsch Stern established a synagogue building fund. In 1879, the assets of the fund already consisted of 3,550 marks, raised through donations. In 1881 the plans became concrete. At a congregational meeting in 1881, various proposals for the acquisition of a suitable site for the synagogue were discussed.

Already in the Middle Ages there was a Jewish community with a synagogue in Karlstadt. The city was planned and founded around 1200 by the Würzburg bishop Konrad von Querfurt on the drawing board. Hans Leopold Müller assumes that Jews were directly involved in the financing and construction of the town. However, this assumption is only supported by circumstantial evidence. There are no written records of the first Jewish community in Karlstadt. It is only known that it was wiped out by the pogrom in the course of the "Rindfleisch-Verfolgung" in 1298.

Last use: kindergarten

Last use: since 1951 house of worship of the Evangelical Lutheran parish

Until 1838 the synagogue was located in the upper part of the house No. 31 (today Nürnberger Straße 16, rear building). This house belonged to Löb Jakob until around 1840. Since 1735 the Jewish community had held its services in this house. In the lower part of the house there was a ritual bath. In the 1820s, the previous synagogue was in a "too ruinous and dilapidated" condition.