In 1819, Maier Strauß (1783-1856), who came from Wollenberg (today Bad Rappenau) and had lived in Hochberg as a "Schutzjude" since 1815, acquired the house from Adam Dohl. Maier Strauß worked as a cattle dealer and bed salesman and was "Jewish church warden" in Hochberg from 1833 to 1853. His son Seligmann Löw Straus worked in his father's business and bought the house from his father in 1841. In 1842, Seligmann Löw founded the bed feather and quilt factory "Straus & Cie" in Ulm, which he moved to Bad Cannstatt in 1862.

The pharmacist Dr. Emil Kahnemann died in 1930. After his death, the widow Margarethe Kahnemann continued to operate G. Steltzner's Einhorn Pharmacy at Große Scharrnstraße 79 alone. In 1936, the pharmacy was "Aryanized" and taken over by Walter Hentschel.

Adolf Wachsmann, owner of the Adler pharmacy. On December 21, 1908, Adolf Wachsmann died after a short serious illness. The Wirwe had to sell the pharmacy to Alfred Hartwig.

Georg Meyer (born December 5, 1888 in Guben; February 3, 1940 in Shanghai) founded the Neuheiten-Kaufhaus department store in Frankfurt after completing a commercial apprenticeship. It was located for rent at Jüdenstrasse 17, corner of Große Scharrnstrasse 18, until 1938. In 1918, he took on his brother Siegfried Meyer as an equal partner and founded a general partnership. He married Maria Bertha Meyer née Schüler (called Betty) with whom he had a daughter, Ursula Meyer. The family lived at Buschmühlenweg 31 (today 41).